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The term molecule does refer to huge molecules and something which comprises more than 1 atom. In the year 1920, this term was coined by Herbal Staudinger. Hence, macromolecules are so large that they are created from more than 10,000 and at times, more than these atoms.

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What is a Macromolecule?

A macromolecule is a huge molecule, like protein. They are commonly collected from smaller subunits’ polymerization known as monomers. Commonly, they are composed of many atoms. A substance which is composed of monomers is known as a polymer.


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The highly common macromolecules present in biochemistry are biopolymers, like proteins, nucleic acids, and carbohydrates besides huge non-polymeric molecules, like macrocycles and lipids, experimental components, like carbon nanotubes and synthetic fibers.

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Kinds of Macromolecules

Commonly, there are 4 chief types of biological macromolecules and they are:

  • Carbohydrates
  • Proteins
  • Nucleic acids
  • Lipids

You can classify them separately in various segments. The principles which govern the association of 3D structure continue to be the same for every one of them. Hence, people can consider them together.

  • Carbohydrates – These are the polymers of hydrogen, oxygen, and carbon. Carbohydrates can be classed as disaccharides, polysaccharides, and monosaccharides. You will find carbohydrates in fruits, sugars, milk, starch, and vegetables. Carbohydrates are a vital source of a person’s healthy diet.
  • Proteins – They are considered polymers of amino acids and proteins comprise the amino group. There wouldn’t be any lipid or carbohydrate in the absence of proteins as the enzymes that are present for their synthesis happen to be proteins themselves.
  • Nucleic acids – These comprise RNA and DNA that are considered polymers of nucleotides. Commonly, nucleotides comprise a phosphate group, a pentose group besides a nitrogenous base group. Every hereditary info remains preserved in the DNA and the DNA gets synthesized into proteins and RNA.
  • Lipids – These are considered a hydrophobic set containing macromolecules. And so, they don’t dissolve in water. Lipids comprise carotenoids, triglycerides, steroids, and phospholipids. They aid in forming the cell membrane.

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Instances of Macromolecules

Some examples of macromolecules are:

  • Synthetic fibers – Spandex, rayon, and nylon comprise macromolecules.
  • Polymers and monomers – Usually, macromolecules are polymers, huge chains of molecular subunits known as monomers. Nucleic acids, proteins, and carbohydrates are present as long polymers. Because of their polymeric behavior and huge size, they are called macromolecules.
  • Genetic transfer – DNA comprises nucleic acids that code for a genetic product. At the time of meiosis, the DNA doesn’t remain as a whole. The nucleotides which remain present are liable for conveying genetic info to the gametes.

The Macromolecules Present in Peanut Butter

The chief biological macromolecules present in peanut butter happen to be nucleic acids, polysaccharides, and proteins. If it is tested for simple sugars then it will test positive.

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